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清道夫受体B类Ⅰ型是高密度脂蛋白受体,主要分布于肝脏和生成类固醇激素的组织。它与高密度脂蛋白以高亲和性结合,还可与天然的低密度脂蛋白、乙酰化低密度脂蛋白、氧化低密度脂蛋白、磷脂酰丝氨酸、阴离子磷脂等结合,对胆固醇和胆固醇酯的代谢起着重要的作用,可影响胞质膜胆固醇的分布,改变膜结构,从而影响多种生理和病理生理功能。
Scavenger receptor class B type I is a high-density lipoprotein receptor, mainly distributed in the liver and the formation of steroid hormone tissue. It binds with high-density lipoprotein with high affinity, but also with the natural low-density lipoprotein, acetylated low-density lipoprotein, oxidized low-density lipoprotein, phosphatidylserine, anionic phospholipid combination of cholesterol and cholesterol ester Metabolism plays an important role, can affect the distribution of cytoplasmic membrane cholesterol, change the membrane structure, thus affecting a variety of physiological and pathophysiological functions.