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本文研究13例糖尿病酮症酸中毒患者血清淀粉酶及其同功酶浓度的变化,且与15名健康者和15例非糖尿病的急性胰腺炎患者做了比较。所有糖尿病酮症酸中毒患者入院时均有明显的高糖血症、酮症酸中毒和血清肌酐浓度升高,但仅7例血清淀粉酶浓度升高(分别为37,38,57,62,144,565和960单位/毫升,正常<25单位/毫升)。该7例于治疗头2天内血清淀粉酶浓度即已转正常。7例高淀粉酶血症中的5例和6例血清淀粉酶正常中的3例有上腹痛。其中3例高淀粉酶血症伴有上腹痛者入院前曾被考虑有胰腺炎。7例高淀粉酶血症中除2例血清碱性磷酸酶浓度稍升高外,均无肝功能不全证据。其中3例高淀粉酶血症测定了淀粉酶/肌酐清除率比值(正常为3.1±1.1％,急性胰腺炎为9.8±3.5％)和血
This article studies 13 patients with diabetic ketoacidosis serum amylase and its isoenzyme concentration changes, and with 15 healthy and 15 non-diabetic patients with acute pancreatitis were compared. All patients with diabetic ketoacidosis had marked hyperglycemia, ketoacidosis and elevated serum creatinine levels at admission, but only seven patients had elevated serum amylase concentrations (37, 38, 57, 62, 144, 565 and 960 units / ml, normal <25 units / ml). The seven cases in the first two days of treatment of serum amylase concentration has turned normal. Five of the seven patients with hyper amylasemia and three of six patients with normal serum amylase had upper abdominal pain. Three cases of hyper amylase with upper abdominal pain were considered pancreatitis before admission. There were no evidence of liver dysfunction except for 2 cases with elevated serum amylase concentration in 7 cases of hyper amylase. In 3 of them, the amylase / creatinine clearance ratio (normal 3.1 ± 1.1%, acute pancreatitis 9.8 ± 3.5%) and blood