目的　探讨中央性神经细胞瘤 (CN)的诊断、治疗及预后。方法　回顾分析我科 1 993～ 2 0 0 0年收治的1 7例CN的临床资料。结果　 1 7例患者发病年龄从 1 7到 47岁不等 ,平均 31 5岁。男女比例为 1 1 3∶1。颅内压增高是本病的主要临床表现。 1 6例行开颅手术 ,其中 4例全切除 ,7例次全切除 ,5例大部分切除。 7例于术后辅以放疗。另 1例于立体定向穿刺活检后行γ 刀治疗。 1 2例随访 6～ 77个月 ,平均 2 8 4个月。 1例行大部分切除而未接受放疗者于术后 8个月因肿瘤复发而死亡 ,其余 1 1例均未见复发。结论　CN通常被认为是一种分化程度较高的良性肿瘤 ,多数病例经手术切除后预后较好 ,对于手术未能全切除、术后有复发或经组织病理学证实有较高增殖活性的病例 ,可行放射治疗 Objective To investigate the diagnosis, treatment and prognosis of central neurocytoma (CN). Methods The clinical data of 17 CN patients treated in our hospital from 1993 to 2000 were retrospectively analyzed. Results The onset age of 1 7 patients varied from 17 to 47 years old, with an average of 31 5 years. The ratio of male to female is 1 1 3: 1. Increased intracranial pressure is the main clinical manifestations of the disease. 16 routine craniotomy, including 4 cases of total resection, subtotal resection in 7 cases, 5 cases were mostly resected. 7 cases were supplemented with radiotherapy after operation. Another case of stereotactic biopsy after gamma knife treatment. 12 cases were followed up for 6 to 77 months, an average of 284 months. A majority of patients who underwent resection but did not receive radiotherapy died of tumor recurrence 8 months after operation, and no recurrence was observed in the remaining 11 cases. Conclusions CN is generally considered to be a benign tumor with a high degree of differentiation. Most cases have a good prognosis after surgical resection. Cases with incomplete proliferative surgery, postoperative recurrence or confirmed by histopathology have higher proliferative activity , Feasible radiotherapy