肺癌是常见的恶性肿瘤之一,其死亡率目前居全身恶性肿瘤之首。虽然肺癌的治疗手段如手术切除、放化疗及生物治疗等在不断进步,但其5年生存率仍不到1 3%。然而,对I期肺癌行手术切除5年生存率可达80 %。因此,改善预后的关键在于早发现、早诊断和及时手术切除[1] 。目前临床发现的 Lung cancer is one of the most common malignancies and its mortality rate is now at the top of all malignant tumors. Although the treatment of lung cancer such as surgical resection, radiotherapy and chemotherapy and biological treatment are making continuous progress, but its 5-year survival rate is still less than 13%. However, the 5-year survival rate of surgical resection of stage I lung cancer up to 80%. Therefore, the key to improving prognosis lies in early detection, early diagnosis and prompt surgical resection [1]. Currently clinically discovered