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临床上为了提高治疗效果,采用中西药结合的方法越来越普遍。但根据临床观察和有关报道,中西药配伍时需注意以下几种情况: 1.朱砂安神丸、梅花点活丹,七厘散、仁丹丸等含汞类中药与碘化钾合剂、溴化钙等卤素类化合物不能同服,否则产生有毒的卤化汞导致赤痢样大便或药源性肠炎。 2.石膏、白矾、龙骨、牛黄解毒丸等与四环素类、大环内酯类抗生素不能同服。此类中药含钙、镁、铁、铝等离子可与四环素分子上的酚羟基、烯酸基形成不溶性的盐或络合物;与大环内酯类药物分子中的大环结构形成复盐,导致药效降低甚至消失。
Clinically, in order to improve the therapeutic effect, the combination of Chinese and Western medicine is becoming more and more common. However, according to clinical observation and related reports, the compatibility of Chinese and Western medicines should pay attention to the following situations: 1. Cinnabar Anshen pills, Plum point live Dan, Qili San, Jen Dan pills and other mercury-containing compounds with potassium iodide, calcium bromide and other halogen Class compounds can not be the same service, or produce toxic mercury halide lead to diarrhea like stool or drug-induced enteritis. 2. Plaster, alum, keel, bezoar detoxification pills and tetracycline, macrolide antibiotics can not be the same service. Such traditional Chinese medicine calcium, magnesium, iron, aluminum ions with the tetracycline molecule phenolic hydroxyl group, the formation of insoluble acid salt or complex; and macrolide molecules in the macrocyclic structure of the formation of double salt, Lead to lower efficacy or even disappear.