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目的探讨过敏性紫癜(HSP)患儿急性期心肌损害的原因、发病机制和预后。方法对152例HSP患儿临床资料进行回顾性分析。结果 152例HSP患儿中有46例合并心肌损害,占30.3%,其中心电图异常27例,占17.8%,主要以ST-T改变、P-R间期延长为主,心肌酶改变32例,占21.1%,混合型患儿心肌损害比例明显增高。结论临床治疗HSP应常规检查心肌酶、心电图,以便及时干预,改善HSP患儿预后。
Objective To investigate the causes, pathogenesis and prognosis of acute myocardial injury in children with Henoch-Schonlein purpura (HSP). Methods The clinical data of 152 cases of HSP were retrospectively analyzed. Results Of the 152 children with HSP, 46 cases had myocardial damage, accounting for 30.3%. The electrocardiogram was abnormal in 27 cases (17.8%). The main changes were ST-T and prolongation of PR interval. The changes of myocardial enzymes were found in 32 cases (21.1%) %, Mixed type of myocardial damage was significantly higher. Conclusion The clinical treatment of HSP should be routine examination of myocardial enzymes, ECG, in order to timely intervention to improve the prognosis of HSP.