论文部分内容阅读
目的：观察龙鹿胶囊治疗少弱精子症的疗效，并探讨其可能的作用机制。方法采用多中心、随机对照的临床研究，将确诊的360例患者随机分为对照组（160例）和治疗组（200例）。对照组服用VitE，100mg，bid；治疗组服用龙鹿胶囊，3粒，tid。两组治疗3个月后，分别检测精液质量（精液量、精子浓度、前向运动精子、精子DFI、精浆SOD）及女方受孕率。结果有330例患者完成了临床研究，治疗组在精液量、精子浓度、前向运动精子、精子DFI、精浆SOD方面较用药前，均有显著的改善（P＜0.05），并且疗效优于对照组（P＜0.05）。结论龙鹿胶囊可提高体内的抗氧化能力，改善精子质量及自然妊娠率，并未见明显不良反应。“,”Objective To observe the efficacy of Longlu Capsule in the treatment of oligoasthenospermia and explore its probable mechanism. Methods Usig the multi-centered randomized controlled study, 360 infertile men with oligoasthenospermia were divided into two groups including the control group (160 cases) and the treatment group (200 cases). The patients in the control group were administrated VitE, 100mg once, bid and the patients in the treatment group were given Longlu Capsule, three pills, tid. After the treatment for 3 months, Semen volume, spermatozoa density, prorsad spermatozoa rate, spermatozoa DFI, seminal SOD, and pregnancy rate were measured. Results A total of 330 patients accomplished the clinical trial. In the treatment group, the index of semen volume, spermatozoa density, prorsad spermatozoa rate, spermatozoa DFI, and seminal SOD, were obviously improved compared to that of pre-treatment (P<0.05). Meanwhile, an obvious amelioration in spermatozoa density, prorsad spermatozoa rate, spermatozoa DFI, seminal SOD, and pregnancy rate were found compared to that of the control group (P<0.05). Conclusion Longlu Capsule can evidently improve the seminal quality and natural pregnancy rate of oligoasthenospermia patients via increasing the anti-oxidant ability.