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Rho亚家族(RhoA,RhoB,RhoC)在细胞信号转导及细胞运动中起重要作用。Rho亚家族蛋白与恶性肿瘤的侵袭与转移有密切关系,其中以RhoC的作用最显著。对Rho蛋白的深入研究有助于进一步判断其在恶性肿瘤侵袭转移中所扮演的角色,为肿瘤的治疗提供新的依据。
The Rho subfamilies (RhoA, RhoB, RhoC) play an important role in cell signaling and cell motility. Rho subfamily protein is closely related to the invasion and metastasis of malignant tumors, of which the role of RhoC is the most significant. In-depth study of Rho protein helps to further determine its role in the invasion and metastasis of malignant tumors, providing a new basis for the treatment of cancer.