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心脏再同步治疗（ CRT）在心力衰竭治疗方面的效果已被广泛证实。随着指南的更新，其治疗的适应证范围不断扩大，更多患者将从中受益。但研究证明，仍有近30％的患者表现为 CRT无应答。由于目前还没有统一的、被普遍认可的 CRT 应答评估标准，CRT治疗效果的评价仍较为混乱。越来越多的研究致力于提高CRT应答率，以更好地预测患者的预后，帮助临床决策。该文试图通过分析总结目前有关CRT无应答的原因，探寻最优的应答评估标准和更好的引导程控优化的方法，为提高CRT应答率提供参考依据。“,”The effects of Cardiac resynchronization therapy ( CRT) in the treatment of heart failure have been widely confirmed.With the guideline update its treatment indications has been expanded ,enabling more patients to benefit from.But some studies show that there is still no response for CRT showed nearly 30% of patients.There is no generally accepted CRT response evaluation standard , evaluation of the CRT treatment effect is relative confused .More and more research is committed to increase the CRT response rate and get better prediction of the prognosis.This paper reviews the recent research findings,tries to provide a reference for finding the optimal assessment of response and control method after operation .