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目的 :调查庚型肝炎病毒 ( HGV)在肾病综合征患儿中的感染分布。 方法 :115例患儿均为我科确诊的原发性肾病综合征住院患儿 ,另取 187例同期上呼吸道感染患儿 ,采取外周血 2 m l,用 RT- PCR方法检测 HGVRNA。 结果 :在 15 5例肾病综合征患儿中有 11例 ( 7.1% )存在 HGV感染 ,在 187例正常对照儿童中仅有 3例( 1.6 % )存在 HGV感染 ,两者具有较明显的差异。 结论 :肾病综合征患儿的 HGV感染率明显高于普通儿童 ,为HGV感染的高危人群
Objective: To investigate the distribution of hepatitis G virus (HGV) infection in children with nephrotic syndrome. Methods: One hundred and fifteen children were hospitalized with primary nephrotic syndrome diagnosed in our department. Another 187 children with upper respiratory tract infection during the same period were taken. Peripheral blood was collected at 2 ml for detection of HGVRNA by RT-PCR. RESULTS: HGV infection occurred in 11 of 15 (7.1%) children with nephrotic syndrome and in 3 of 187 normal control children (1.6%) with HGV infection, with significant differences between the two. Conclusion: The prevalence of HGV infection in children with nephrotic syndrome is significantly higher than that in normal children, which is at high risk for HGV infection