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目的对手足口病患儿的实验室检测结果进行分析,使用痰热清注射液与炎琥宁联合应用治疗手足口病患儿,分析其对手足口病的临床治疗效果。方法选取2013年1月至2014年10月122例非重症手足口病患儿的咽拭子、肛拭子和粪便样本,首先用RT-PCR法对病毒核酸进行肠道病毒通用型、肠道病毒71型(EV71)和科萨奇病毒A组16型(CA16)进行检测;再将手足口病患儿按照随机数字表方法随机分为治疗组(n=61)和对照组(n=61),治疗组给予痰热清注射液与炎琥宁联合治疗,对照组给予病毒唑治疗,观察记录患儿治疗后退热时间、皮疹消退时间和住院时间。分析痰热清注射液与炎琥宁联合应用对手足口病治疗的临床效果。结果 122例非重症手足口病患儿EV71阳性93例,CA16阳性22例。治疗组患儿的退热时间、皮疹消退时间和住院时间均明显短于对照组(P均<0.01)。结论痰热清注射液与炎琥宁联合应用可明显缩短病程,见效快,能有效减轻患儿痛苦,疗效确切。
Objective To analyze the laboratory test results of hand-foot-mouth disease in children and treat children with hand-foot-mouth disease by Tanreqing injection and Yan-hu-ning, and to analyze its clinical effect on hand-foot-mouth disease. Methods Throat swabs, anal swabs and stool samples were collected from 122 non-critically ill HFMD patients from January 2013 to October 2014. The viral nucleic acids were detected by RT-PCR. (EV71) and Coxsackievirus A (type 16) (CA16). Randomly divided children with HFMD were divided into treatment group (n = 61) and control group (n = 61) ). The treatment group was treated with Tanreqing Injection combined with Yanhuning. The control group was treated with ribavirin. The antipyretic time, rash subsidence time and hospital stay after treatment were recorded and recorded. To analyze the clinical effect of Tanreqing Injection combined with Yanhuning in the treatment of foot-mouth disease. Results Of the 122 non-critical hand-foot-mouth disease patients, 93 were positive for EV71 and 22 were positive for CA16. Antipyretic time, rash subsidence time and hospitalization time in the treatment group were significantly shorter than those in the control group (all P <0.01). Conclusion Tanreqing injection combined with Yan Hu Ning can significantly shorten the course of the disease, quick, can effectively reduce the pain of children, the exact effect.