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纯巨核细胞再生障碍性血小板减少症(AATP)的血液学特征是血小板减少、骨髓巨核细胞减少或缺如、而粒红两系很少异常。目前该症被越来越多的血液病学工作者所关注。通过回顾性分析,现将我院1980年1月～1989年8月收治的18例AATP报道如下。诊断标准目前尚无统一的AATP诊断标准,本组病例按陈义平等提出的诊断标准:(1)严重的血小板减少症伴出血症状;(2)骨髓增生活跃,巨核细胞明显减少,粒红两系基本正常;(3)可伴有失血性贫血;(4)白细胞计数和分类正常或基本正常;(5)肝、脾、淋巴结不肿大;(6)排除先天性巨核细胞再生障碍性血小板减少症。
The hematologic features of pure megakaryocyte aplastic thrombocytopenia (AATP) are thrombocytopenia, diminished or absence of bone marrow megakaryocytes, and few grazing of both maize. The disease is currently being concerned by more and more hematology workers. Through retrospective analysis, now in our hospital from January 1980 to August 1989 18 cases of AATP reported below. Diagnostic criteria There is no uniform AATP diagnostic criteria, the patients according to Chen Yi-ping and other diagnostic criteria proposed: (1) severe thrombocytopenia with bleeding symptoms; (2) bone marrow hyperplasia, significantly reduced megakaryocytes, (3) can be associated with hemorrhagic anemia; (4) white blood cell count and classification normal or almost normal; (5) liver, spleen, lymph nodes does not enlarge; (6) to exclude congenital megakaryocyte aplastic platelet Reduce disease.