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目的 :研究急性胰腺炎患者 IL- 6、TNFα分泌情况及其临床意义。方法 :选择 30例急性胰腺炎患者和 2 8例健康对照 ,用生物学方法检测血浆中 IL- 6、TNFα的水平。结果 :急性胰腺炎患者血浆中 IL- 6、TNFα分别为 ( 76.4± 1 0 .1 ) k u/L、60 .7%± 1 2 .3% ,均高于正常对照组 ( 2 0 .8±6.1 ) k u/L、1 2 .4%± 4.7% ,随疾病的恢复逐渐趋于正常 ( 2 8.5± 9.1 ) k u/L、1 8.8%± 6.4%。结论 :急性胰腺炎患者血浆中的 IL- 6、TNFα水平均高于正常组 ,说明二者参与这一炎症过程
Objective: To study the secretion of IL-6 and TNFα in patients with acute pancreatitis and its clinical significance. Methods: Thirty patients with acute pancreatitis and 28 healthy controls were selected to detect the levels of IL-6 and TNFα in the plasma by biological methods. Results: The plasma levels of IL-6 and TNFα in patients with acute pancreatitis were (76.4 ± 1.01) ku / L and 60.7% ± 1.23%, respectively, which were higher than those in the normal control group (208 ± 6.1) ku / L, 12.4% ± 4.7%, with the recovery of the disease tends to normal (2 8.5 ± 9.1) ku / L, 1 8.8% ± 6.4%. Conclusion: The plasma levels of IL-6 and TNFα in patients with acute pancreatitis are higher than those in normal group, indicating that both are involved in this inflammatory process