为了阐明针刺镇痛在中枢神经系统内的作用方式,我们选择了头面部痛觉传入的第二级神经元部位——三叉神经脊束核进行研究。首先须要在这个神经核中记录出只接受疼痛感觉的细胞的诱发放电。在此基础上,再进一步探索电针穴位对于这些痛细胞放电的作用及其作用方式,希望以此对针麻原理有所说明。 我们前一段工作曾报导了在猫三叉神经脊束核尾端记录到只对伤害性刺激起反应的单个细胞诱发放电。这些放电为高频放电,潜伏期较长,刺激阀值较高,可被镇痛剂 To elucidate the mode of action of acupuncture analgesia in the central nervous system, we investigated the trigeminal nucleus of the trigeminal nucleus, the second-level neuronal component of head-facial pain perception. First of all, it is necessary to record in this nucleus the evoked discharge of cells that only receive pain perception. On this basis, further explore the role of acupuncture points for these pain cells discharge and its mode of action, hoping to explain the principle of acupuncture. It has been reported in our previous work that single cells evoked discharges that respond only to nociceptive stimuli are recorded at the caudal ends of cat trigeminal nerve bundles. These discharges are high-frequency discharges, with longer incubation periods and higher stimulus thresholds, which can be analgesic