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目的:优选烧伤灵涂膜的最佳醇提取工艺。方法:以浸膏得率和大黄素、盐酸小檗碱提取率为评价指标,用多指标综合评分法进行数据处理,采用正交试验考察乙醇体积分数、乙醇用量、回流时间、回流次数对提取效果的影响。结果:烧伤灵涂膜最佳醇提取工艺为:加6倍量的95%乙醇,加热回流3次,每次2 h。结论:该提取工艺设计合理,结果可靠,提取效果较好。
OBJECTIVE: To optimize the best alcohol extraction process for burn wound coating. Methods: The extraction rate of emodin and berberine hydrochloride were used as the evaluation indexes. The data were processed by the multi-index comprehensive score method. The orthogonal test was used to investigate the effects of ethanol volume fraction, ethanol dosage, reflux time, Effect of effect. Results: The optimum alcohol extraction process of burn wound coating was as follows: add 6 times 95% ethanol and heat reflux 3 times for 2 h each time. Conclusion: The extraction process is reasonable in design, reliable results and good extraction.