本研究运用人类高分辨染色体显微切割、ＰＣＲ技术获得的８ｑ２４．１带特异性探针池，构建了该区带的ｐＵＣ１９文库，从中筛选出４８个含ＣＡ重复顺序的微小卫星ＤＮＡ的克隆，已完成１２个克隆的序列分析，发现了一个世界上至今未曾报道过的、在正常人群中已检出１１个等位片段的、杂合度在中国汉族人群和美国盎格鲁撤克逊族人群中分别达０．８４和０．８３的高度多态的微小卫星ＤＮＡ（编号：Ｄ８Ｓ７Ｆ），经ＰＣＲ检测人鼠杂种细胞系列，证实其来源于人８号染色体。 In this study, we constructed a pUC19 library of 8q24.1 band-specific probe pool obtained from human high-resolution chromosome microdissection and PCR, and screened 48 microsatellite DNA clones with CA repeats, A sequence analysis of 12 clones has been completed and found that one heterozygous heterozygosity has been detected in the normal Chinese population and in the Chinese Han population and the American Anglo-Saxon population respectively Up to 0.84 and 0.83 highly polymorphic DNA microarray (No .: D8S7F). The human and mouse hybrid cell lines were detected by PCR, which was confirmed by the human chromosome 8.