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本文报告456例鼻部皮肤癌。其中以50岁至60岁年龄组发病率最高,30岁以前发病者仅1%。性别差异不大。鳞癌发生于男性者多于女性。暴露于日光下及表浅放疗为最常见的病因。456例患者中基底细胞癌396例(87%)、鳞癌49例(10.7%)、基底-鳞癌7例(1.5%)、黑色素瘤2例(0.4%)、恶性神经鞘膜瘤和汗腺腺癌各1例(0.2%)。基底细胞癌多发生于鼻翼、鼻尖和鼻根;鳞癌多发生于鼻侧缘和鼻小柱。放射治疗可控制和治疗多数鼻部癌,但也往往成为有害致病因素,本文报告病例51%由面部皮肤病(如:痤疮、毛发病、湿疹,酒渣鼻、角化病等)进行不适当的放疗而导致癌变。396例基底细胞癌中仅
This article reports 456 cases of nasal skin cancer. Among them, the highest incidence rate was in the 50 to 60 year old age group, and only 1% in the 30 year old age group. Little difference in gender. Squamous cell carcinoma occurs in more men than women. Exposure to sunlight and superficial radiotherapy are the most common causes. Among 456 patients, 396 were basal cell carcinoma (87%), 49 squamous cell carcinomas (10.7%), 7 basal-squamous carcinomas (1.5%), 2 melanomas (0.4%), malignant nerve sheath tumors, and sweat glands. One case of adenocarcinoma (0.2%). Basal cell carcinoma mostly occurs in the nasal wing, nasal tip and nasal root; squamous cell carcinoma occurs mostly in the nasal margin and the columella. Radiation therapy can control and treat most nasal cancers, but it is also often a detrimental pathogenic factor. 51% of the cases reported in this report are caused by facial skin diseases (eg acne, hair disease, eczema, rosacea, keratosis, etc.). Proper radiotherapy causes canceration. Only 396 cases of basal cell carcinoma