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本组80例中,男50例,女30例。年龄2个月至15岁。便培养痢疾杆菌均阳性,按国内规定标准分型及疗效判定。观察方法:用磷霉素钙口服治疗,150～200mg/kg/日,分4次口服,5天为1疗程,配以口服补液盐及对症治疗,均不投予其他抗生素。治疗结果:主要症状消失所需平均日数为:发热1.04天,腹痛及/或里急后重1.63天,便次增多2.03天,肉眼大便性状改变1.68天。便培养痢疾杆菌转阴平均日数为1.32天。治愈76例,好转4例。优于国内应用痢特灵+TMP+SG,吡哌酸,苦参,TMP,PST,复方洗必泰,复方新诺明加复方苦参及复方新诺明等组的疗效。43株分离的痢疾菌株均作了药敏试
80 cases in this group, 50 males and 30 females. Age 2 months to 15 years old. They were positive for dysentery bacilli, according to the provisions of the standard type and efficacy of the decision. Observations: Fosfomycin calcium oral treatment, 150 ~ 200mg / kg / day, 4 times orally, 5 days for a course of treatment, together with oral rehydration salts and symptomatic treatment, were not given other antibiotics. Treatment outcome: The average number of days required for disappearance of major symptoms was 1.04 days with fever, 1.63 days with abdominal pain and / or tenesmus, an increase of 2.03 days, and a 1.68-day change in the physical stool. The average day of dysentery bacilli culture was 1.32 days. 76 cases were cured, improved in 4 cases. It is superior to the domestic application of furazolidone + TMP + SG, pipemidic acid, Sophora flavescens, TMP, PST, chlorhexidine compound, compound sulfamethoxazole and compound sulfamethoxazole and other groups. 43 strains of dysentery strains were made drug sensitivity test