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目的研究髋臼各组成部分环状骨突生长板的生长速度。方法选用年龄3~4周的新西兰大白兔20只,采用伸膝位长腿石膏管型固定的方法,将幼兔的左下肢固定8周,分别于固定后4、6、8周拍摄X线片直至出现髋臼发育不良兔动物模型7只。将分离出的发育不良髋臼制作病理组织学切片,运用图像分析技术量化髋臼发育不良动物模型中髋臼各组成部分(髂骨、坐骨、耻骨)的环状骨突生长板的生长速度。结果实验组发育不良的髋臼各骨中,坐骨环状骨突生长板生长速度最大,其次为髂骨,耻骨环状骨突生长板生长速度最低;对照组发育正常的髋臼各骨中,髂骨环状骨突生长板生长速度最大,其次为坐骨,耻骨环状骨突生长板生长速度最低。结论不同方向的力学刺激对髋臼各骨的生长发育具有重要影响。
Objective To study the growth rate of annular osteoprogenitor growth plate in all components of acetabulum. Methods Twenty New Zealand white rabbits aged 3 to 4 weeks were selected. The left lower limbs of the rabbits were fixed for 8 weeks with long leg plaster tube fixation. The X-rays were taken at 4, 6, 8 weeks after fixation Until the appearance of acetabular dysplastic rabbit animal model 7. Histopathological sections of dysplastic acetabulum were isolated and histopathological sections were visualized using image analysis techniques to quantify the growth rate of the ring osteopontin growth plate in all acetabular components (ilium, ischial, pubic bone) in an acetabular dysplastic animal model. Results In experimental group, the growth of osteochondral growth plate was the largest in all dysplastic acetabular bones, followed by ilium and the pubic symphysis was the lowest. In normal control acetabular bone, The growth of ilium ring bone growth plate is the largest, followed by the ischium, pubic ring bone growth plate growth rate lowest. Conclusion Mechanical stimulation in different directions has an important influence on the growth and development of acetabular bone.