1病例介绍病例1女,44岁。因“反复皮疹3+年,发现尿蛋白升高15 d”于2013年5月入院。3+年前患者无明显诱因出现双下肢大片皮疹,直径约2 mm,皮疹对称分布,水肿,突起于皮肤表面,部分融合,伴渗出性红斑,局部皮温增高,无破溃及脱屑,无明显瘙痒,无日光照射后加重表现。3+年来皮疹反复,并出现眼睑及颜面肿胀,以晨起时明显,活动后缓解,无双下肢水肿。15 d前在当地医院皮肤科住院,查尿常规示:尿蛋白定 1 case description Case 1 female, 44 years old. Due to “Repeated rash 3+ years and found that urinary protein increased 15 d ” in May 2013 admitted. 3 years ago, no obvious incentive for patients with large double-limb rash, diameter of about 2 mm, rash symmetrical distribution, edema, protruding from the skin surface, partial fusion, with exudative erythema, local skin temperature increased, no ulceration and scaling , No obvious itching, no increase after sun exposure. 3+ years rash repeated, and there eyelid and facial swelling, clear early morning activity, ease after exercise, unparalleled lower extremity edema. 15 days before the hospital in the local hospital dermatology, check urinary routine shows: urinary protein set