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绒毛膜细胞直接法制备染色体是一种新的早期产前诊断方法。本文用改良方法直接制备染色体,减少染色体丢失现象,获得较满意效果。本法资料表明分裂相出现率为100%,可进行核型分析者达94%,适用于6~11周孕妇,特别是孕7周左右效果更好。与绒毛膜细胞培养法相比,受母体细胞污染的可能性小,结果更可靠。此方法简单、快速、效果好、易于普及,对产前诊断提供了有效措施。
Chromosome direct preparation of chromosomes is a new method of early prenatal diagnosis. In this paper, a direct method for the preparation of chromosomes to reduce chromosome loss, to obtain more satisfactory results. The data show that the incidence of split phase was 100%, karyotyping can be up to 94% for 6 to 11 weeks pregnant women, especially about 7 weeks pregnant effect is better. Compared with choriocarcinoma culture method, the possibility of contamination by maternal cells is small, and the result is more reliable. The method is simple, rapid, effective and easy to popularize, providing effective measures for prenatal diagnosis.