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成年动物全脾切除对免疫功能有无影响尚有争议。本实验对成年大鼠人工造成脾门破裂后,在脾动脉结扎的基础上行全脾切除及不同类型的脾保留手术(脾缝合修补或脾部分切除或自体脾组织移植)。术后第4个月测各组溶血素抗体及迟发型过敏反应。结果表明:全脾切除或不同类型的脾保留组的溶血素抗体及迟发型过敏反应与正常对照组相比,无明显差别。
Spleen resection of adult animals have no effect on immune function is controversial. In this study, after splenectomy was induced in adult rats, splenectomy and splenectomy were performed on the basis of splenic artery ligation (spleen suture repair or partial splenectomy or autologous spleen transplantation). After the first 4 months, hemolysin antibody and delayed-type hypersensitivity reaction were measured. The results showed that there was no significant difference between hemolysin antibody and delayed-type hypersensitivity reaction in splenectomy or different types of splenic retention group compared with normal control group.