旋光活性胺在有机化合物的拆分和立体化学的研究方面有着广泛的应用。这种胺有的来源于天然产物,如某些生物碱(马钱子碱、番木鳖碱、奎宁、辛可宁等),也可由合成产物经拆分得到,如L-或D-α-苯乙胺。此外,还可用某些易得的天然产物作原料来制备。我们在此介绍的L-盖胺就是从便宜易得的L-(艹孟)醇(薄荷醇)经氧化、肟化及还原三步反应制得的。 Optically active amines have a wide range of applications in the resolution and stereochemistry of organic compounds. Some of these amines are derived from natural products such as certain alkaloids (strychnine, strychnine, quinine, cinchonine, etc.) and may also be obtained from the synthesis of products such as L- or D-α- Phenethylamine. In addition, some readily available natural products can be used as raw materials to prepare. The L-caplamine we introduce here is obtained by a three-step oxidation, oximation and reduction reaction of a cheap and readily available L-menthol (menthol).