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采用小剂量个体化MTX方案治疗未破裂异位妊娠21例。治疗前血β-HCG范围在167～26000IU/L,治疗时连续测定血β-HCG用于监测个体化用药量,范围为45～90mg,平均61.5mg。19例治愈,成功率为90.4％;失败两例为间质部妊娠发现较晚。证明本方案对早期异位妊娠治疗安全有效,且能保留生育能力,关键在于早诊断。本组腹部B超检查有38.1％为阴性,因此应结合病电,连续测定血β-HCG,综合分析,尤其对存在异位妊娠好发因素者应提高警惕。
Twenty-one cases of unruptured ectopic pregnancy were treated with small dose of individualized MTX regimen. The blood β-HCG ranged from 167 to 26000 IU / L before treatment, and blood β-HCG was continuously measured during treatment to monitor the individualized dosage, ranging from 45 to 90 mg with an average of 61.5 mg. 19 cases were cured, the success rate was 90.4%; failed two cases of interstitial pregnancy was found late. Proves that this program is safe and effective for the treatment of early ectopic pregnancy, and can retain fertility, the key lies in the early diagnosis. The group of abdominal ultrasound B-38.1% were negative, it should be combined with electropathy, continuous determination of blood β-HCG, a comprehensive analysis, especially for those who have ectopic pregnancy prone factors should be vigilant.