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目的 了解江苏省人群中甲 1型流感抗体水平及其流行病学特征 ,为流感的预防提供科学依据。方法 利用微量半加敏血凝抑制试验方法检测江苏省不同地区 (南京、徐州、无锡 )、不同自然人群〔养禽场农工、养猪场农工、靠近 (<5 0 0m)及远离 (>10 0 0m)养殖场居民〕中甲 1型流感抗体水平 ,结合流行病学资料进行统计分析。结果 江苏省人群甲 1型流感抗体阳性率为 32 96 % ,护体保护率为 7 36 % ,抗体GMT为 1∶7 96。甲 1型抗体水平存在地区、年龄差异 ,徐州地区抗体水平高于其它两地区 ,2 5岁以下年龄组抗体水平高于其他年龄组 ,其中 15岁以下年龄组抗体阳性率和抗体GMT最高。甲 1型抗体水平 2 0 0 0年和 2 0 0 1年比较无显著性差异。结论 江苏省人群中甲 1型流感抗体水平偏低 ,全省仍存在局部爆发或流行的潜在危险。
Objective To understand the antibody level and epidemiological characteristics of Influenza A (H1N1) in Jiangsu Province and provide a scientific basis for the prevention of influenza. Methods The method of micro-hemostatic inhibition test was used to detect the difference between different areas (Nanjing, Xuzhou, Wuxi) and different natural populations (farm workers in poultry farms, farm workers in pig farms, near (<500m) 0 0m) farm residents] in a type 1 influenza antibody levels, combined with epidemiological data for statistical analysis. Results The positive rate of Influenza A (H1N1) antibody in Jiangsu Province was 32 96%, that of body protection was 7 36%, and that of antibody GMT was 1:7 96. The antibody level of type A antibody was different in different regions and age groups. The antibody level in Xuzhou was higher than that in the other two regions. The antibody level in the age group of under 25 years old was higher than other age groups. The antibody positive rate and antibody GMT in age below 15 years old were the highest. There was no significant difference in the level of type A antibody between 2000 and 2001. Conclusion The level of influenza A antibody in Jiangsu population is low, and there is still a potential danger of local outbreak or epidemic in the province.