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目的 :调查Hp感染在健康医务人员与非医务人员之间的流行状况。方法 :对我院部分体检的医务人员及来我院体检的长沙市某些企事业单位职工共 5 0 2人 ,用金标免疫斑点法检测血清Hp抗体 ,对Hp抗体阳性者再用免疫印迹法进行分型。结果 :医务人员组与非医务人员组Hp感染率分别为 6 7.2 %和 5 8.5 % (P <0 .0 5 ) ,Ⅰ型感染率分别为 2 3.4 %和 15 .9% (P <0 .0 5 ) ;内科消化专科医师护士组与内科其他专科医师护士组Hp感染率分别为 73.7%和 6 5 .9% (P >0 .0 5 ) ,Ⅰ型感染率分别为 31.2 %和 17.1% (P >0 .0 5 ) ;医师组与护士组Hp感染率分别为 6 5 .5 %和 6 7.2 % (P >0 .0 5 ) ,Ⅰ型感染率分别为 2 1.8%和 2 8.4 % (P >0 .0 5 ) ;医师护士组与实验室和后勤工作人员组Hp感染率分别为 6 6 .2 %和 6 3.7% (P >0 .0 5 ) ,Ⅰ型感染率分别为 2 4 .7%和 2 0 .6 % (P >0 .0 5 )。结论 :医务人员Hp感染的危险性明显高于非医务人员 ,且感染的细菌毒力较强 ,医务人员应加强自我防护 ;Hp感染的分型对临床诊治可能有一定的指导意义。
PURPOSE: To investigate the prevalence of Hp infection among health workers and non-medical workers. Methods: A total of 502 workers and staff of some enterprises and institutions in Changsha City who came to our hospital for physical examination were screened for serum Hp antibodies by gold standard immunoblotting and Western blotting on Hp antibody positive patients Law for classification. Results: The infection rates of Hp between medical staff and non-medical staff were respectively 6 7.2% and 8.55% (P <0.05). The infection rate of type I was 23.4% and 15.9% respectively (P <0. The prevalences of Hp infection were 73.7% and 65.9% (P> 0.05), respectively. The infection rates of type I were 31.2% and 17.1% respectively, (P> 0.05). The infection rates of Hp in the physician and nurse groups were 65.5% and 62.2% respectively (P> 0.05), the infection rates of type I were 21.8% and 28.4% (P> 0.05). The infection rates of Hp between physician nurses and lab staff and logistics workers were respectively 6.62% and 6.3% (P> 0.05), and the infection rates of type I were 2 4 .7% and 20.6% (P> 0.05). Conclusion: The risk of Hp infection among medical staffs is obviously higher than that of non-medical staffs, and the bacterial infection is strong. Medical staff should strengthen self-protection. The typing of Hp infection may have some guiding significance for clinical diagnosis and treatment.