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目的探讨宫颈脱落液基细胞学检查(TCT)联合人乳头瘤病毒检测(HPV-DNA)诊断宫颈癌的临床意义。方法选取2012年5月至2015年5月间海南省文昌市人民医院收治的100例宫颈癌患者,分别单独行TCT检测、单独HPV-DNA检测、HPV-DNA+TCT检测,比较3种检测方法的诊断结果。结果 HPV-DNA+TCT检测宫颈癌的阳性率为81.0%,显著高于单独TCT检测的51.0%和单独HPV-DNA检测的55.0%,差异有统计学意义(P<0.05);单独TCT与单独HPV-DNA检测的阳性率间差异无统计学意义(P>0.05)。结论 TCT和HPV-DNA联合诊断宫颈癌阳性符合率较高,具有显著的临床应用价值。
Objective To investigate the clinical significance of cervical exfoliated liquid-based cytology (TCT) combined with human papillomavirus (HPV-DNA) in the diagnosis of cervical cancer. Methods 100 patients with cervical cancer who were admitted to Wenchang People’s Hospital of Hainan Province from May 2012 to May 2015 were divided into three groups by TCT test, HPV-DNA test alone and HPV-DNA + TCT test alone The diagnosis results. Results The positive rate of HPV-DNA + TCT in detecting cervical cancer was 81.0%, which was significantly higher than 51.0% in TCT alone and 55.0% in HPV-DNA alone (P <0.05) The positive rate of HPV-DNA test showed no significant difference (P> 0.05). Conclusion The positive coincidence rate of TCT and HPV-DNA in the diagnosis of cervical cancer is high, which has significant clinical value.