奥沙利铂作为第3代铂类抗癌药在消化道肿瘤等实体肿瘤的内科治疗领域中应用广泛,其不良反应主要表现为神经毒性及骨髓抑制等方面,对于奥沙利铂所致过敏反应,临床上并不少见,近年来国内报道多例。其中严重性过敏性休克甚至猝死的也有报道[1],一项大型随机对照临床研究表明,奥沙利铂致过敏反应的发生率为10.3%,其中Ⅲ、Ⅳ度过敏反应的发生率为2.9%[2]。鉴于目前国内临床医务工作者对奥沙利铂的潜在致死性过敏的重视和认识不够,本文拟对近年来本科在奥沙利铂用药过程中出现的过敏反应做出分析,并总结该反应的处理方法,以利于今后出现类似反应,能及时作出相应处理,减 Oxaliplatin as the third generation of platinum anticancer drugs in the gastrointestinal cancer and other solid tumors in the field of medical treatment is widely used, the adverse reactions mainly as neurotoxicity and bone marrow suppression, etc., for the allergy caused by oxaliplatin Response, clinical is not uncommon in recent years, many cases reported in China. The severity of anaphylactic shock and even sudden death have also been reported [1]. A large randomized controlled clinical study showed that the incidence of allergic reactions induced by oxaliplatin was 10.3%, and the incidence of allergic reactions of grade Ⅲ and Ⅳ was 2.9 %[2]. In view of the current domestic clinical medical workers on the potential mortality of oxaliplatin allergy attention and awareness is not enough, this article intends to undergraduate oxaliplatin in the course of the course of allergic reactions occurred during the analysis and summary of the reaction Treatment methods to facilitate similar reactions in the future, to make the appropriate treatment in time, minus