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红霉素对G~+菌如金黄色葡萄球菌,溶血性链球菌,肺炎球菌,白喉杆菌有一定作用,对G~-菌如脑膜炎双球菌、淋球菌、大肠杆菌也有一定作用,对支原体,螺旋体等也有较强的抑制作用,有些对青霉素耐药的菌株而对红霉素敏感.是广谱高效抑菌药物.我科常用红霉素治疗支原体肺炎及耐药菌肺炎,疗效较佳.但红霉素不良反应较多.临床常用维生素B_6.解除其不良反应.我科自1997年初起,运用山茛菪碱(654-2)解除红霉素不良反应取得满意疗效,现报告如下:
Erythromycin G ~ + bacteria such as Staphylococcus aureus, hemolytic streptococcus, pneumococcus, diphtheria bacilli have some effect on G ~ - bacteria such as meningococcus, Neisseria gonorrhoeae, Escherichia coli also have a role in the mycoplasma , Spirochetes, also have a strong inhibitory effect, some strains resistant to penicillin and erythromycin sensitive broad-spectrum antibacterial drugs are widely used in our department erythromycin treatment of mycoplasma pneumonia and resistant bacteria pneumonia, better curative effect .But erythromycin more adverse reactions.Clinical commonly used vitamin B_6 to relieve the adverse reactions.Our department since early 1997, the use of anisodamine (654-2) to remove the adverse reactions of erythromycin obtained satisfactory results are as follows :