为比较卡托普利、依那普利、苯那普利、西拉普利引起咳嗽的情况和性别、抽烟对咳嗽的影响，本文将服用卡托普利、依那普利、苯那普利、西拉普利的病人分为４组，统计每组中产生咳嗽副作用的病例的百分数，用χ２检验来检验各组间发生咳嗽的差异性。各组引起咳嗽的比例分别为卡托普利５０％（１０／２０１）、依那普利６７％（３／４５）、苯那普利３９％（７／１８０）、西拉普利４８％（５／１０４）。并发现，男性患者咳嗽发生率３０％（１２／３９６），女性患者咳嗽发生率９７％（１３／１３４）；吸烟病人咳嗽发生率７０％（８／１１５），不吸烟病人咳嗽发生率４１％（１７／４１５）。本研究发现卡托普利、依那普利、苯那普利、西拉普利在产生咳嗽的副作用方面无显著差异（Ｐ＞００５），女性病人较男性病人在服用血管紧张素转换酶抑制剂时咳嗽副作用发生的比例更高，吸烟病人较不吸烟病人发生咳嗽副作用的比例更高 In order to compare the effects of captopril, enalapril, benazepril, cilazapril on cough and sex and smoking on cough, this paper will take captopril, enalapril, benazepril Lee, Cilazapri patients were divided into 4 groups, statistics in each group the percentage of cases of cough side effects, using the χ2 test to test the differences between groups cough. The rates of cough in each group were captopril 5  0% (10/201), enalapril 6  7% (3/45), benazepril 3  9% (7/180) Cilazapril 4  8% (5/104). The incidence of cough was 30% (12/396) in male patients and 97% (13/134) in female patients. The incidence of cough in smoking patients was 70% (8/115), no smoking The incidence of cough in patients was 4  1% (17/415). This study found no significant differences in the side effects of captopril between captopril, enalapril, benazepril, cilazapril and females (P> 0.05). Female patients switched from angiotensin-converting The incidence of cough side effects was higher with enzyme inhibitors, and the proportion of smokers with smokers was higher for smokers than for nonsmokers