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目的探讨左氧氟沙星治疗急性肾盂肾炎的疗效及安全性。方法将我院2010年1月-2012年6月收治的60例急性肾盂肾炎患者随机分为观察组和对照组各30例。观察组给予左氧氟沙星注射液治疗,对照组给予氨苄青霉素注射液治疗。比较两组患者的临床疗效。结果观察组的总有效率为100%,显著高于对照组的76.67%,差异有统计学意义(P<0.05)。结论左氧氟沙星治疗肾盂肾炎的临床疗效显著,药物安全、可靠、不良反应小,值得临床推广和应用。
Objective To investigate the efficacy and safety of levofloxacin in the treatment of acute pyelonephritis. Methods Sixty patients with acute pyelonephritis admitted in our hospital from January 2010 to June 2012 were randomly divided into observation group (30 cases) and control group (30 cases). The observation group was given levofloxacin injection and the control group was given ampicillin injection. The clinical efficacy of the two groups was compared. Results The total effective rate of the observation group was 100%, which was significantly higher than that of the control group (76.67%), the difference was statistically significant (P <0.05). Conclusion Levofloxacin treatment of pyelonephritis clinically significant effect, drug safety, reliability, adverse reactions, worthy of clinical promotion and application.