患者女,3岁,住院号8514因肝脾肿大。二年余前来我院就诊。患儿出生后五个月因腹泻前往南京市儿童医院就诊,住院体检发现肝脾肿大,治疗一周后腹泻仃止,但肝、脾继续肿大,曾多次就诊,均未明确诊断。患儿经常腹泻感冒。一岁时曾患营养不良,治疗后好转。患儿常鼻衄,局部压迫后即能止血。两下肢经常出现瘀斑,但可自行消退。否认结核及肝炎病史。患儿系第一胎第一产,足月顺产,母乳喂养,八个月出牙,一岁会走路,说话,智力发育尚好。父母体健,为非近亲结婚,家中无 Female patient, 3 years old, hospital number 8514 due to hepatosplenomegaly. More than two years to our hospital. Five months after birth, the children went to Nanjing Children’s Hospital for treatment of diarrhea. Liver and spleen enlargement were found on in-hospital examination. After one week of treatment, diarrhea was stopped. However, the liver and spleen continued to enlarge and had multiple visits. No definite diagnosis was made. Children often have diarrhea and cold. One year old suffered from malnutrition, improved after treatment. Children often nosebleed, local oppression that can stop bleeding. Ecchymosis often appears on both lower extremities, but may subside on its own. Denied the history of tuberculosis and hepatitis. Pediatric first-birth first child, term full-term, breastfeeding, eight months of teething, walking one year old, talking, mental development is still good. Healthy parents, non-relatives married, no home