近年来,农村医院普遍存在着滥用糖皮质激素的现象,把这类药物(主要是地塞米松)当成退热药、止痛药应用.有的病人竟自己长期大量服用.因此,由此类药物引起的药源性疾病逐渐增多.我院1989年1月～1994年12月,收治了100例由糖皮质激素引起的消化性溃疡病人,现报告如下.1 临床资料100例中,男性68例,女性32例,男女之比为2.1:1.年龄最大78岁,最小15岁.经纤维胃镜确诊者66例,经X线钡餐造影确诊者28例,穿孔后手术发现者6例.这些病人均否认在服用糖皮质激素前有溃疡病史,并有服用植皮质激素类药物史.从服药后到发生溃疡症状最长6个月,最短者20天. In recent years, widespread abuse of glucocorticoid in rural hospitals phenomenon, such drugs (mainly dexamethasone) as antipyretics, painkillers. Some patients actually take their own long-term large doses .Therefore, such drugs Caused by drug-induced disease gradually increased in our hospital from January 1989 to December 1994, 100 patients treated by glucocorticoid peptic ulcer patients are reported as follows.1 Clinical data of 100 cases, 68 males , 32 females, male to female ratio was 2.1: 1. The oldest was 78 years old, the youngest was 15. 66 cases were diagnosed by fiber endoscopy, 28 cases were diagnosed by X-ray barium scan and 6 cases were found by perforation surgery. Have denied the history of ulcers before taking glucocorticoids, and taking corticosteroids history from the medication to the occurrence of ulcers up to 6 months, the shortest of 20 days.