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目的对小儿双清颗粒治疗小儿急性上呼吸道感染的临床效果进行分析。方法 250例急性上呼吸道感染患儿,将其随机分为两组,治疗组128例,对照组122例,对照组采用西药治疗,即在0.9%氯化钠注射液中加入利巴韦林、青霉素钠氯化钠或头孢唑林钠静脉滴注,治疗组在对照组治疗基础上加用小儿双清颗粒治疗,疗效评定标准参照《中药新药临床研究指导原则》。结果治疗组治愈75例,占58.59%,显效32例,占25.00%,有效16例,占12.50%,无效5例,占3.91%,总有效率96.09%;对照组治愈55例,占45.08%;显效26例,占21.31%,有效22例,占18.03%,无效19例,占15.57%,总有效率84.43%,治疗组明显优于对照组,差异有统计学意义(P<0.05)。结论小儿双清颗粒治疗小儿急性上呼吸道感染较单独西药治疗效果好,安全性高,值得临床上应用推广。
Objective To analyze the clinical effect of Shuangqing granule in children with acute upper respiratory tract infection. Methods 250 cases of children with acute upper respiratory tract infection were randomly divided into two groups: 128 cases in the treatment group and 122 cases in the control group. Western medicine was used in the control group, namely ribavirin in 0.9% sodium chloride injection, Penicillin sodium chloride or cefazolin sodium intravenous infusion, the treatment group in the control group based on the treatment plus pediatric Shuangqing Granules treatment, curative effect evaluation criteria with reference to “new drug clinical research guidelines.” Results The treatment group cured 75 cases, accounting for 58.59%, 32 cases were markedly effective, accounting for 25.00%, effective in 16 cases, accounting for 12.50%, ineffective in 5 cases, accounting for 3.91%, the total effective rate was 96.09%; control group 55 cases, accounting for 45.08% ; Effective in 26 cases, accounting for 21.31%, effective in 22 cases, accounting for 18.03%, ineffective in 19 cases, accounting for 15.57%, the total effective rate 84.43%, the treatment group was significantly better than the control group, the difference was statistically significant (P <0.05). Conclusion Pediatric Shuangqing Granule treatment of children with acute upper respiratory tract infection than Western medicine alone is effective, safe and worthy of clinical application.