论文部分内容阅读
[目的]考察胃黏膜中幽门螺杆菌(Hp)形态对胃炎病理性特征影响。[方法]回顾性分析400例行胃黏膜检查患者的临床资料,依据是否存在Hp感染分为感染组(237例)和未感染组(163例),并将感染组依据Hp形态将胃炎患者分为单纯球形组(62例)和伴螺旋状组(175例)。比较2组患者病理性形态差异,并用统计学软件进行分析。[结果]2组患者性别、炎症类型和严重程度比较差异有统计学意义(P<0.05)。单纯球形组患者女性比例显著高于伴螺旋状组(P<0.05)。单纯感染组患者炎症活动率和间质淋巴细胞数量差异有统计学意义(P<0.05)。[结论]Hp对胃黏膜具有致病性,且男性患者感染患有更高危害的螺旋状幽门杆菌概率更高。
[Objective] To investigate the effect of Helicobacter pylori (Hp) morphology in gastric mucosa on pathological features of gastritis. [Methods] The clinical data of 400 patients with gastric mucosa were retrospectively analyzed. According to the presence of Hp infection, the patients were divided into infection group (237 cases) and uninfected group (163 cases). According to the Hp morphology, Simple spherical group (62 cases) and spiral group (175 cases). Pathological differences between the two groups were compared and analyzed using statistical software. [Results] There were significant differences in gender, type of inflammation and severity between the two groups (P <0.05). The proportion of women in the simple spherical group was significantly higher than that in the spiral group (P <0.05). There were significant differences in inflammatory activity rate and interstitial lymphocyte count in patients with simple infection (P <0.05). [Conclusion] Hp is pathogenic to gastric mucosa, and male patients are infected with Helicobacter pylori with higher risk.