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对左室心肌梗塞(MI)是否会直接影响右室功能,至今尚有争议。本实验观察大鼠左室MI时右室dp/dt max的改变及其与左室dp/dt max和梗塞范围(IS)间的关系。结果发现冠脉结扎后1天,在左室dp/dt max显著降低的同时,右室dp/dt max也显著降低,且与左室dp/dt max呈显著的直线正相关,而与IS呈显著的直线负相关。在冠脉结扎后3天时,左室dp/dt max有显著恢复,但仍低于对照水平,而右室dp/dt max已恢复正常,且与左室的dp/dt max和IS间不再具有显著的直线相关关系。由此证明;在大鼠左室MI早期,右室收缩性能可受到直接影响,影响的程度与IS及左室收缩性能降低的程度相关;但当左室收缩性能恢复到一定程度时,这种影响消失。
Right ventricular myocardial infarction (MI) will have a direct impact on right ventricular function, is still controversial. In this study, we observed the changes of right ventricular dp / dt max and its relationship with left ventricular dp / dt max and infarct size (IS). The results showed that dp / dt max of right ventricle was significantly decreased at 1 d after coronary ligation, while dp / dt max of left ventricle was significantly decreased, while dp / dt max of right ventricle was significantly positively correlated with d Significant linear negative correlation. At 3 days after coronary ligation, left ventricular dp / dt max recovered significantly but remained below the control level, while dp / dt max in the right ventricle returned to normal with no difference from dp / dt max and IS in the left ventricle Has a significant linear correlation. Proved that in rats with early left ventricular MI, right ventricular systolic performance can be directly affected, the degree of IS and left ventricular systolic performance decreased; However, when left ventricular systolic performance restored to a certain extent, this The impact disappears.