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[目的]探讨无创性鼻(面)罩双水平气道正压通气(BiPAP)治疗化学气体中毒性肺水肿的疗效。[方法]对48例化学气体中毒导致肺水肿的患者随机分为两组,治疗组(23例)予以无创性鼻(面)罩双水平气道正压通气(BiPAP)联合甲强龙治疗,对照组(25例)予以常规面罩吸氧联合甲强龙治疗。观察通气前后呼吸频率(RR)、心率(HR)、氧分压(PaO2)及二氧化碳(PaCO2)、胸部CT变化及临床症状的改善情况。[结果]治疗组呼吸频率(RR)、心率(HR)、氧分压(PaO2)胸部CT变化及临床症状的改善明显优于对照组(P<0.05)[结论]无创性鼻(面)罩双水平气道正压通气(BiPAP)治疗化学气体中毒性肺水肿疗效满意。
[Objective] To investigate the curative effect of noninvasive nasal (bilateral) mask bi-level positive airway pressure (BiPAP) in the treatment of toxic gas poisoning pulmonary edema. [Methods] Forty-eight patients with pulmonary edema caused by chemical poisoning were randomly divided into two groups. The treatment group (23 cases) was treated with BiPAP combined with methylprednisolone (non-invasive nasal mask) The control group (n = 25) was treated with conventional mask oxygen therapy combined with methylprednisolone. Respiratory rate (RR), heart rate (HR), partial pressure of oxygen (PaO2) and carbon dioxide (PaCO2), chest CT changes and clinical symptoms before and after ventilation were observed. [Results] The improvement of chest CT and heart rate (RR), heart rate (HR) and oxygen tension (PaO2) in the treatment group were significantly better than those in the control group (P <0.05) Biphasic positive airway pressure (BiPAP) treatment of toxic gas poisoning pulmonary edema satisfactory results.