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目的:为了判断血浆灌流对中毒有机磷中毒的治疗效果。方法:将52例重度有机磷中毒患者随机分为2组,治疗组26例行血浆灌流治疗,对照组26例行血液灌流治疗,比较治疗组和对照组在昏迷时间、胆碱酯酶活力恢复时间、住院时间、病死率、对血小板的影响的等方面的差异。结果:治疗组患者昏迷时间、胆碱酯酶活力恢复时间、住院时间、病死率、对血小板的影响与对照组比较差异有统计学意义(P<0.05)。结论:血浆灌流治疗重度有机磷中毒的疗效显著。
Objective: To determine the therapeutic effect of plasma perfusion on organophosphate poisoning. Methods: Fifty-two patients with severe organophosphate poisoning were randomly divided into two groups. The treatment group was treated by plasma perfusion, the control group was treated by hemoperfusion. Compared with the control group, the cholinesterase activity was recovered in the treatment group and the control group Time, hospital stay, fatality rate, effects on platelets and so on. Results: The treatment group coma time, recovery time of cholinesterase activity, hospital stay, mortality, the impact of platelets compared with the control group was statistically significant (P <0.05). Conclusion: The therapeutic effect of plasma perfusion on severe organophosphate poisoning is significant.