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目的:评价双水平无创通气(BiPAP)对慢性阻塞性肺疾病(COPD)并肺性脑病的临床疗效。方法:27例COPD并肺性脑病患者在综合治疗基础上用BiPAP治疗,观察治疗前后血气分析与临床症状的变化。结果:24例患者治疗后,血气分析与临床症状较治疗前明显改善,余3例患者病情加重,1例自动出院,2例死亡。结论:BiPAP对COPD呼吸衰竭并肺性脑病具有积极的治疗意义。
Objective: To evaluate the clinical efficacy of bi-level noninvasive ventilation (BiPAP) in patients with chronic obstructive pulmonary disease (COPD) and pulmonary encephalopathy. Methods: Twenty-seven patients with COPD and pulmonary encephalopathy were treated with BiPAP on the basis of comprehensive treatment. The changes of blood gas analysis and clinical symptoms before and after treatment were observed. Results: After treatment, the blood gas analysis and clinical symptoms were significantly improved in 24 patients. More than 3 patients were exacerbated, 1 patient was discharged automatically and 2 patients died. Conclusion: BiPAP has a positive therapeutic effect on COPD respiratory failure and pulmonary encephalopathy.