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目的:探讨奥诺先(DEX)对女性乳腺癌患者术后化疗所引起心脏毒性的防治效果。方法:将患者随机分为治疗组和对照组,对术后患者采取EPI+DTX的辅助化疗方法,对治疗组患者加用DEX(10:1),观察两组治疗前后的临床指标。结果:经治疗,治疗组与观察组患者的c Tnt有明显变化,治愈率分别为78.1%和92.3%。结论:针对女性乳腺癌患者而言,DEX+EPI+DTX方案对其术后化疗的心脏保护有显著效果。
Objective: To investigate the preventive and therapeutic effects of Ornix (DEX) on cardiotoxicity induced by postoperative chemotherapy in female breast cancer patients. Methods: The patients were randomly divided into treatment group and control group. Adjuvant chemotherapy with EPI + DTX was used in the postoperative patients. DEX (10: 1) was used to treat the patients in the treatment group. The clinical indexes before and after treatment were observed. Results: After treatment, cTnt in treatment group and observation group had obvious changes, the cure rates were 78.1% and 92.3% respectively. CONCLUSIONS: DEX + EPI + DTX regimen has a significant effect on postoperative chemotherapy for cardioprotection in women with breast cancer.