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目的:研究血清同型半胱氨酸(Hcy)水平与中青年前循环脑梗死的关系。方法:选取中青年前循环脑梗死生存者176例为前循环脑梗死组(观察组),正常健康体检40例为对照组,测定并比较两组血清中Hcy水平的变化。结果:观察组血清中Hcy水平非常显著高于对照组(P<0.01)。观察组颈动脉狭窄者血清Hcy水平非常显著高于颈动脉正常者(P<0.01),并有随着颈动脉狭窄程度加重,血清中Hcy水平增高的趋势;治疗后血清中Hcy水平非常显著降低于治疗前(P<0.01)。结论:血清中高Hcy水平是中青年前循环脑梗死的危险因素之一,药物治疗可降低血清中Hcy水平。
Objective: To study the relationship between serum homocysteine (Hcy) levels and cerebral infarction in middle-aged and young patients. Methods: A total of 176 patients with cerebral infarction in the middle-aged and young adults were selected as the anterior circulation cerebral infarction (observation group). 40 healthy controls were selected as the control group. The levels of Hcy in serum were measured and compared. Results: The level of Hcy in the observation group was significantly higher than that in the control group (P <0.01). The level of Hcy in the observation group was significantly higher than that in the normal carotid artery (P <0.01), and the level of Hcy in serum increased with the severity of carotid stenosis. The level of Hcy in the observation group was significantly lower Before treatment (P <0.01). Conclusion: The high serum homocysteine level is one of the risk factors of cerebral infarction in middle-aged young people. Drug treatment can reduce the level of Hcy in serum.