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目的 :观察糖尿病对大鼠性激素水平影响及对性腺器官的损害。方法 :用放射免疫法测定血清性激素水平 ,测定性腺器官的重量并以性腺重量与体重的比值计算性腺系数。结果 :D组和ID组大鼠睾丸、附睾、前列腺、精囊重量均明显低于C组 ,D组大鼠前列腺及精囊系数低于C组 ,D组和ID组大鼠血清睾酮水平明显低于C组。结论 :糖尿病对成年大鼠性腺器官具有明显的损害作用 ,且使睾丸分泌睾酮的能力明显下降。
Objective: To observe the effects of diabetes on sex hormones and damage to gonadal organs in rats. Methods: Serum sex hormone levels were determined by radioimmunoassay, gonadal organ weights were determined and the gonadal factors were calculated as the ratio of gonad weight to body weight. Results: The weight of testis, epididymis, prostate and seminal vesicle in D group and ID group were significantly lower than those in C group. The prostate and seminal vesicle coefficient in D group were lower than those in C group. The serum testosterone levels in D group and ID group were significantly lower than those in C group Group C Conclusion: Diabetes mellitus has significant damage to gonadal organs in adult rats, and the ability of testes to secrete testosterone is obviously decreased.