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rn目的探讨多囊卵巢综合征(PCOS)患者血清性激素水平、皮质醇(Cor)变化及临床意义。方法 50例PCOS患者(PCOS组)和47例正常妇女(对照组)在早晨空腹采血,采用电化学发光法和放射免疫分析法测定血清硫酸脱氢表雄酮(DHEA)、性激素结合球蛋白(SHBG)、17羟孕酮(17-OHP)、雌二醇(E2)、睾酮(T)、泌乳素(PRL)、黄体生成素(LH)、促卵泡刺激素(FSH)及Cor等指标。结果 PCOS组患者血清DHEA、17-OHP、T和LH均明显高于对照组(P“,”Objective To explore the changes and clinical significance of serum sex hormones and cortisol(Cor) in the patients with polycystic ovary syndrome(PCOS).Methods The serum sex hormones and Cor were detected by electrochemiluminescence and radioimmunoassay in 50 patients with PCOS and 47 healthy people(normal controls).Results Serum levels of dehydro-epiandrosterone sulfate(DHEA),17-hydroxyprogesterone(17-OHP),testosterone(T) and luteinizing hormone(LH) were higher,but those of sex hormone binding globulin(SHBG),prolactin(PRL) and Cor were lower,in PCOS patients than those in the controls(P<0.01).Conclusion Combined detection of DHEA,17-OHP,SHBG,T,PRL,LH and Cor is helpful for the diagnosis and therapy in the patients with PCOS.