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目的观察CT引导下~(125)I粒子植入治疗晚期肺鳞癌的治疗效果。方法应用~(125)I粒子植入术治疗晚期肺鳞癌40例,总结CT引导下~(125)I粒子植入术的疗效和并发症。结果术后1个月随访,CR 24例,PR 12例,SD 3例,PD 1例,总有效率为90.0%.术后3个月随访,CR 25例,PR 9例,SD 5例,PD 1例,总有效率为85.O%.术后KPS评分较术前明显升高(P<0.05)。结论 CT引导下~(125)I粒子植入治疗晚期肺鳞癌疗效确切,可显著提高患者生存质量,是一种安全、简便、微创的治疗手段。
Objective To observe the therapeutic effect of ~ (125) I particle implantation guided by CT on advanced squamous cell carcinoma of the lung. Methods 40 cases of advanced squamous cell carcinoma were treated with ~ (125) I seed implantation and the curative effect and complication of ~ (125) I particle implantation guided by CT were summarized. Results One month follow-up, there were 24 CR, 12 PR, 3 SD and 1 PD. The total effective rate was 90.0% .After 3 months follow-up, there were 25 CR, 9 PR and 5 SD, PD in 1 case, the total effective rate was 85. O% .KPS score after operation was significantly higher than that before operation (P <0.05). Conclusion CT-guided implantation of ~ (125) I particles in the treatment of advanced squamous cell carcinoma of lung is effective and can significantly improve the quality of life of patients. It is a safe, simple and minimally invasive treatment.