论文部分内容阅读
目的确定寨卡病毒在泰国传播的免疫学证据。方法对可能感染寨卡病毒的人群进行血清学调查,共对21名未明确病因的急性发热患者进行免疫学检查,检查内容包括寨卡病毒、登革热、日本脑炎和基孔肯雅热抗原免疫印迹分析。结果 21份血清样本中有20份显示至少存在一个抗原免疫反应阳性,7份样本显示所有抗原均呈阳性。其中两份血清样本仅显示寨卡病毒抗原阳性,而没有其它抗原检测阳性结果。结论本研究首次证实了寨卡病毒已经在泰国传播,但疑似病例如何感染寨卡病毒并传播尚需进一步调查。
Objective To determine the immunological evidence for the spread of Zika virus in Thailand. Methods A serological survey was conducted on a group of people who may be infected with Zika virus. A total of 21 patients with acute fever who did not have a definite cause were immunologically examined. The contents of the tests included Zika virus, dengue fever, Japanese encephalitis and chikungunya fever antigen Imprinting analysis. Results Twenty of the 21 serum samples showed at least one immunoprecipitation of the antigen and seven of the samples showed positive for all the antigens. Two of the serum samples showed positive for Zika virus only, but no positive result was detected for the other antigens. Conclusions This study, for the first time, confirms that Zika virus has been transmitted in Thailand. However, the suspected cases of Zika virus infection and transmission still need further investigation.