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目的 对卵巢癌腹水相关因素进行分析 ,探讨其与临床的关系。方法 收集我院 1993年 1月～ 1998年 1月收治的卵巢癌有腹水患者 72例 ,回顾性分析卵巢癌腹水的相关因素 ,并对腹水分别进行细胞学检查找癌细胞、CA12 5测定和染色体检查。结果 40岁以上卵巢癌腹水中癌细胞检出率为 73 .5 % ;腹水发生率为 81.9% ;腹水癌细胞阳性Ⅲ期以上者占 91.2 % ;腹水量 >10 0 0ml者腹水中癌细胞阳性率明显增高 ;卵巢表面有癌组织浸润或卵巢自发破裂者 ,腹水癌细胞阳性率为 6 4.7% ;大网膜、肠管、横隔转移者腹水中易出现癌细胞 ;腹水癌细胞阴性组 ,卵巢癌腹水中CA12 5平均值为(32 4.94± 5 2 7.6 4)kU/L ,而腹水癌细胞阳性者腹水CA12 5平均值为 (5 172 .6 4± 1432 .6 1)kU/L ;腹水癌细胞阳性组与腹水癌细胞阴性组染色体检测非整倍体出现率均在 2 / 3以上。结论 对卵巢癌有腹水者行腹水癌细胞、染色体及CA12 5常规测定 ,可提高卵巢癌诊断的正确性
Objective To analyze the related factors of ascites in ovarian cancer and to explore its relationship with clinical. Methods Seventy-two patients with ascites were collected from January 1993 to January 1998 in our hospital. The related factors of ascites in ovarian cancer were retrospectively analyzed. Cytological examination of ascites was performed to find cancer cells, CA125 assay and chromosome an examination. Results The detection rate of cancer cells in ascites of ovarian astrocytoma over the age of 40 was 73.5%, the incidence of ascites was 81.9%, that of the ascites cells was 91.2%, and the amount of ascites was more than 100ml The rate was significantly higher; ovarian surface cancer or spontaneous rupture of ovarian cancer, ascites cancer cell positive rate was 6 4.7%; omentum, intestine, transseptal ascites prone to cancer cells; ascites cancer cell negative group, ovarian The mean value of CA12 5 in cancerous ascites was (32 4.94 ± 5 2 7.6 4) kU / L, while the average value of ascites CA12 5 in ascites carcinoma cells was (5 172.44 ± 1432.61) kU / L; ascites The incidence of aneuploidy in chromosomes of cancer cell positive group and ascites cancer cell negative group were more than 2/3. Conclusion Ascites in ovarian cancer patients with ascites cancer cells, chromosome and CA12 5 routine determination can improve the diagnosis of ovarian cancer