论文部分内容阅读
抗血小板药物与溶栓剂联合溶栓治疗深静脉栓塞治疗机制的研究山西医学院第一附属医院（０３０００１）李正中，贺抗，温柱德，李思晋我们联合应用尿激酶（ＵＫ）、前列腺素Ｅ１（ＰＧＥｌ）和中药，对５６例深静脉栓塞（ＤＶＴ）病人进行治疗并检测凝血及纤溶指标，以探讨治疗机制及监测指标。材料与方法一、材料：ＵＫ：２万单位／Ａｍｐｌｅ，南京大学制药厂提供。１０万单位／Ａｍｐｌｅ，太原生化制药厂。ＰＧＥ１：白求恩医科大学制药厂。６０％泛影葡胺，上海信谊药厂。二、病例选择：７１例深静脉栓塞（ＤＶＴ）病人。随机分为二组进行治疗。治疗前均经９９ｍＴｃ－ＲＢＣ，ＥＣＴ血管显像及静脉造影确诊。①ＵＫ治疗组：５４例５６肢体，男２６例，女２８例；年龄２２～７８岁（４８．５±１５．９２）。病程２天～３年。５０例左下肢栓塞，２例左上肢，２例双下肢栓塞。②对照组：１５例。男７例，女８例。年龄２９～６８岁（４１．３±２０．６）。病程６月～１０年。三、治疗方案：①治疗组：ＵＫ２０００００Ｕ／日。静脉滴注，３小时滴完，每日一次，同时滴注ＰＧＥ１２００ｎｇ／日及中药通脉汤口服，１０天为一疗程。根据病情治疗２～３疗程。两疗程间休息３～５大。②对照组：１０例静
Antiplatelet drugs and thrombolytic agents combined with thrombolytic therapy of deep vein thrombosis treatment mechanism of the First Affiliated Hospital of Shanxi Medical University (030001) Li Zhengzhong, He Kang, Wen Zhu De, Li Si Jin we combined urokinase (UK), prostaglandin E1 (PGE1) and traditional Chinese medicine (TCM). 56 patients with deep venous thrombosis (DVT) were treated and coagulation and fibrinolysis were measured to explore the therapeutic mechanism and monitoring indicators. Materials and methods First, the material: UK: 20,000 units / Ample, Nanjing University Pharmaceutical Factory. 100,000 units / Ample, Taiyuan Biochemical Pharmaceutical Factory. PGE1: Bethune Medical University Pharmaceutical Factory. 60% diatrizoate, Shanghai Xin Yi Pharmaceutical Factory. Second, the case selection: 71 cases of deep venous thrombosis (DVT) patients. Randomly divided into two groups for treatment. Before treatment were confirmed by 99mTc-RBC, ECT angiography and venography. ①UK treatment group: 54 cases of 56 limbs, 26 males and 28 females; aged 22 to 78 years (48.5 ± 15.92). Course of 2 days to 3 years. 50 cases of left lower extremity embolism, 2 cases of left upper extremity and 2 cases of double extremity embolism. ② control group: 15 cases. 7 males and 8 females. Age 29 to 68 years (41.3 ± 20.6). Duration of 6 months to 10 years. Third, treatment options: ① treatment group: UK200000U / day. Intravenous drip, drip 3 hours, once daily, while drip PGE1200ng / day and traditional Chinese medicine Tongmai Tang oral, 10 days for a course of treatment. According to the disease treatment 2 to 3 courses. Two courses of rest 3 to 5 large. ② control group: 10 cases of static