浆细胞主要是B淋巴细胞经抗原刺激后,经过一系列的分化增殖转化而来[1]。临床上常见浆细胞增多的疾病如:多发性骨髓瘤、浆细胞白血病,其浆细胞主要出现于外周血和骨髓中。现有一孤立性浆细胞瘤病例,胸水中出现大量浆细胞,有核细胞数>50%,实属罕见,现报导如下。1临床资料患者,男性,81岁,因“反复咳嗽咳痰30年,加重1天”入院。10年前,患者出现活动后气急,曾诊 Plasma cells are mainly B lymphocytes stimulated by antigens, after a series of differentiation and proliferation from the transformation [1]. Clinically common plasma cell diseases such as: multiple myeloma, plasma cell leukemia, the plasma cells mainly in peripheral blood and bone marrow. The existing cases of solitary plasmacytoma, pleural effusion in a large number of plasma cells, the number of nucleated cells> 50%, it is rare, are reported as follows. 1 Clinical data Patients, male, 81 years old, because of “repeated cough and sputum for 30 years, aggravating 1 day ” admission. Ten years ago, the patient showed ankle after the event, had been diagnosed