肾小管性酸中毒是代谢性酸中毒引起的一种综合症。1935年由 Lightwood 氏首先描述,1946年 Albright 等确定它的病原发生在肾小管,但以后此症在名称及分类方面比较混乱。近年有人根据此病的病理生理改变,把此病分为近端肾小管型及远端肾小管型两种类型。二者都可以是原发或继发,这样可以澄清过去资料中对此病命名及分类上的一些混乱。 Renal tubular acidosis is a syndrome caused by metabolic acidosis. First described by Lightwood in 1935, Albright et al. Determined in 1946 that the pathogen occurred in the tubules, but later the disorder was confusing in terms of name and classification. In recent years, some people according to the pathophysiology of the disease, the disease is divided into proximal tubule and distal tubule two types. Both can be primary or secondary, which can clarify some of the confusion in the past about the name and classification of the disease.