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目的：探讨胃粘膜相关淋巴瘤的临床病理特点。方法：收集22例胃原发性恶性淋巴瘤.应用MALT概念进行形态学及免疫组化分析。结果；本级资料显示临床以中年人多见．男女性别之比为1.4：1。病变好发于胃窦、体部。22例经免疫组化证实均为B细胞性淋巴瘤。其中6例病理形态学呈典型MALT淋巴瘤，13例呈不典型MALT淋巴瘤。3例肿瘤由单一高度恶性中心母细胞样细胞组成，其中2例内可见LEL现象和浆细胞浸润。结论：胃原发性B细胞性淋巴瘤均为MALT淋巴瘤。单一星高度恶性图像的淋巴瘤可能是MALT淋巴瘤转化的一个阶段。
Objective: To investigate the clinicopathological features of gastric mucosa-associated lymphoma. METHODS: Twenty-two cases of primary malignant lymphoma of the stomach were collected. Morphological and immunohistochemical analyses were performed using the MALT concept. The results show that the clinical data is more common in middle-aged people. The ratio of male to female is 1.4:1. Lesions occur in the antrum and body. Twenty-two cases were confirmed by immunohistochemistry as B-cell lymphoma. Among them, 6 cases were typical MALT lymphomas, and 13 cases were atypical MALT lymphomas. Three tumors consisted of a single high-grade malignant mother cell-like cell, of which two cases showed LEL phenomenon and plasma cell infiltration. Conclusion: Gastric primary B-cell lymphomas are all MALT lymphomas. A single-satellite high-grade malignant lymphoma may be a stage in the transformation of MALT lymphoma.